Prostate Cancer Types And The Tissues Invaded

July 20, 2009 by  
Filed under Prostate Cancer

Most people are not aware of this, but there actually are many types of prostate cancer that could be present in many different parts of the prostate. Most folks simply settle for the prostate adeno carcinoma because it is the most common type of this cancer that there is, and it occurs in no fewer than 95% percent of diagnosed cases. Being the most widespread it has become synonymous with the term.

The precursor to prostate malignant tumor is a Prostatic Intraepithelial Neoplasia (PIN), which is found in many different locations within the prostate. It however does not invade the surrounding tissue, or form tumor masses, or cause any symptoms. As a matter of fact, it may eventually vanish; remain unchanged, as opposed to progressing to from prostate type of cancer as most people assume that it does. If it does grow into a malignancy, it may take as much as ten years and maybe even more. To that end, even the experts in the field cannot agree on the magnitude of the risk for prostate cancer in men with the prostatic intraepithelial neoplasia.

The most common cancer of the prostate, the adenocarcinoma, is generally in the peripheral (main glandular) zone of the prostate. ‘Adeno’ in the term refers to ‘a gland’, while ‘carcinoma’ is about ‘cancers in the epithelial cells,’ which are essentially cells that surround body organs or glands.

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It begins when normal semen-secreting prostate gland cells mutate into cancer cells. Initially, small clumps of cancer cells stay with the normal prostate glands, but over time they begin to multiply and spread to the surrounding prostate tissue (the stroma) forming a tumor, eventually growing large enough to invade nearby organs and even further away ones.

A small cell carcinoma of the prostate gland is the type of cancer that is made up of small round cells, and typically forms at nerve cells. Often this is the very aggressive type of prostate cancer that is not easy to detect because it does not raise the PSA levels in the patient’s blood. By the time it can be diagnosed, it would have reached a rather advanced stage. It is also the type of this condition that can metastasize to the brain of the patient.

A third variation of prostate cancer is the squamous cell carcinoma type, which is non glandular in nature but which also does not often result in a spike of prostate specific antigens in the patient. The squamous cell carcinoma is also very aggressive and difficult to detect until the later stages, meaning it is also hard to treat as well.

Naturally there are other rarer forms of this disease such as sarcomas and transitional cell carcinomas. And naturally, the rarer the prostate cancer types, the more difficulty they tend to present.

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