Bone Metastasis of Prostate Cancer – Important Tips That Many Don’t Know

September 23, 2011 by  
Filed under Prostate Cancer Stages

Advanced prostate cancer occurs when the malignancy of the cells of the prostate gland has migrated out of the prostate through the bloodstream and lymphatic system and is now move around the body to other locations all around the body. Such a spread, or metastasis, of the disease for some reason happens to have an affinity for the skeletal system so that the bones in the body of the patient are often attacked the worst. 

Bone metastasis of prostate cancer occurs when the cancerous cells travelling through the body fluids break of and attach themselves to the bone, commencing to multiply rapidly and uncontrollably until the disease has taken over completely. Prostate cancer is ordinarily a slow growing adenocarcinoma, but by the time it advances to bone metastasis it usually isn’t so slow anymore.

The metastasis causes regions of higher concentration to occur in the bone, and regions of lower concentration also. These show up in ribonucleic bone scans as hot spots and cold spot, which could be misleading because most people are prone to thinking that one of them is better or safer than the other. Neither is, because they work together to cause the bones of the patient to fracture in what could be construed to be a spontaneous way.

Bone metastasis also causes bone pain which begins as the cancer grows on the bone and continues through the bone fracturing.

Early stage disease cancer be cured, but not advanced prostate cancer; by the time the disease advances to bone metastasis by the way, all hope of curing the condition is more or less gone. It can be treated though, and effectively. Such a level or phase of the disease is generally one in which the quality of life of the patient drops drastically, so that treatment is often aimed at improving quality of life for the patient, and prolonging his life in the process. Managing the bone pain is also definitely an objective, as is slowing the progression of the disease, all of which are actually possible.

Some processes and treatments for bone metastasis of prostate cancer are still being studied but some are available already. For one, bisphosphonates can help to deal with the pain, as can abiterone acetate – although this latter medication is still in clinical trials. Hormonal therapy may slow disease progression, but if the cancer is resistant to hormone treatments, then chemotherapy will have to do. Radiation therapy can treat all phases of the disease anyhow, so it also applies, but if all else fails, at least the narcotics (opioid pain relievers like morphine) can do the honors.

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