Researchers Discover New Clue Liking Prostate Cancer with Lower Urinary Tract Symptoms (LUTS)

January 9, 2013 by  
Filed under Prostate Cancer News

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Researchers from the Mayo Clinic in Rochester, Minn. USA have identified a new clue linking lower urinary tract symptoms (LUTS) with prostate cancer.

The details of the study conducted on eligible men between 1990 and 2010 have been published in the online edition of the European Urology journal.

Jody A. Charnow reported these details in a post published January 8, 2013 in the Renal & Urology News website. The details of this new research have been highlighted below:

Previously described associations between lower urinary tract symptoms (LUTS) and prostate cancer (PCa) may not be due to an underlying shared biologic etiology or causative mechanism, but rather increased diagnostic intensity among men whose LUTS comes to the attention of physicians, researchers reported online in European Urology.

Christopher J. Weight, MD, of Mayo Clinic in Rochester, Minn., and colleagues followed a representative population-based cohort of 1,922 men aged 40-79 years from 1990 until 2010 with interviews, questionnaires, and abstracting of medical records for prostate outcomes. The researchers identified 168 men treated for LUTS. The median follow-up was 11.8 years.

Of the eligible men, 55% enrolled in the study. Men treated for LUTS were 2.4 times more likely than those not treated for LUTS to undergo a prostate biopsy. Men younger than 65 years who were treated for LUTS were 2.3 times more likely to be diagnosed with PCa, whereas those older than 65 were not. Men with self-reported LUTS were not more likely to undergo biopsy or be diagnosed with PCa.

The authors acknowledged that their study was limited by a lack of histologic or PSA data for the cohort. Source.

Conclusively, the above article hints on the link between LUTS and Prostate Cancer.

Although there are some limitations as noted by the authors of the study, researchers may still find the information relevant to carry out further studies that will eventually validate the link completely.

The pointers to the link cannot be denied. The full details of the study can be accessed from the online European Urology publication.

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