Article on Direct Correlation between Advancement of Prostate Cancer and Enzymatic Activity of Integral Mitochondrial Membrane Protein Published

January 24, 2013 by  
Filed under Prostate Cancer News

A visiting professor of biochemistry in High Point University, NC has published an article that details the direct correlation between the advancement of prostate cancer and the enzymatic activity of an integral mitochondrial membrane protein.

Dr. Eric Lewis published his work in the “Journal of Biological Chemistry”. Details of the publication and other facts have been highlighted in the following online extract:

Dr. Eric Lewis, visiting assistant professor of biochemistry, recently published work in the high-impact “Journal of Biological Chemistry.”

His work, titled “The Enzymatic Activity of Apoptosis Inducing Factor Supports Energy Metabolism Benefiting the Growth and Invasiveness of Advanced Prostate Cancer Cells,” details the direct correlation between the advancement of prostate cancer and the enzymatic activity of an integral mitochondrial membrane protein.

“Every cell in our body has the ability to become cancer,” Lewis says. “However, the underlying, biochemical progression of many types of cancer is poorly understood. These studies detail a direct connection between the advancement of prostate cancer and the activity of an enzymatic protein which seemingly controls a tumorigenic, metabolic, cellular change. The implications of these studies could lead to diagnostic and preventative treatments for hundreds of thousands of new patients with prostate cancer.”

Dr. Lewis continues saying, “This work, which is being built upon in a collaborative effort, is allowing undergraduates at High Point University to explore the biochemical aspects of cancer.  As a department and university as a whole, we feel that each student should have the opportunity to explore the intricacies of such a wide-spreading and impactful topic.”

Lewis, who co-authored the article with colleagues at Wake Forest School of Medicine and the University of Michigan, has been published twice in the past two years in “Biochemistry” and the “Journal of Biological Chemistry” – both prestigious journals. Source.

Conclusively, details from the above work helps those interested in prostate cancer to get more understanding of the biochemical aspect of the disease.

It would not only be invaluable to undergraduates in High Point University but to students and researchers elsewhere.

More details on what this article discusses can be accessed in the “Journal of Biological Chemistry”.

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