Transfer Factor Prostate Cancer – The Importance in Treatment

Transfer factors are the immune messenger molecules found in all higher animals in white blood cells, colostrum, and eggs. They are often given credit for the perpetuation of species by transferring immunity against many pathogens that would otherwise kill the offspring. The importance of the transfer factor in cancer treatment was first considered by American Nobel laureate Paul Berg during an experiment in the last century, but as of today there are several clinical studies that are considering wider approaches in the application of the polypeptide for treating various forms of cancer, and specifically in prostate cancer intervention.

In one study, taking into account that late stage prostate cancers are hugely considered to be incurable and usually unresponsive to hormonal therapy, the transfer factor was considered for treating stage D3 hormone refractory prostate cancers (HRPCa). A team of 15 doctors led by Pizza G. of the Immunodiagnosis and Immunotherapy Unit, S. Orsola-Malpighi Hospital, Bologna, Italy released a preliminary report stating first the obvious ? that conventional treatments for prostate cancer are unsuccessful, and the survival rate of stage D3 prostate cancer patients is poor; and then the prospective ? that there is the possibility of the existence of humoral and cell-mediated immunity (CMI) against prostate cancer tumor-associated antigens (TAA).

All of the tests on the transfer factor were carried out in vitro so far, but the results were not nearly so bad. Of the fifty patients entered into the study, follow-up showed complete remission in 2 patients, partial remission in 6, and no progression of metastatic disease in 14, making a total of twenty two patients who responded to the transfer factor prostate cancer treatment with a median survival of 126 weeks higher than the survival rates reported in the literature for patients of the same stage.

This might not sound like a huge step in the right direction, but these were patients that were believed to be well on their way out, because stage IV hormone refractory prostate cancer is not considered to be curable for the most part. Naturally this has increased curiosity in the potency of the transfer factor as a treatment for the malignancy, and more research is going into finding out precisely what the edge is.

Another study that looked into the effect of transfer factor on tumor-associated immunity and tumor growth of the Dunning R-3327G prostate adenocarcinoma was carried out on rats. In preliminary findings, a poorly differentiated, fast-growing, androgen sensitive, and poorly metastatic tumor of the Dunning R-3327 rat PCa, G subline only minor positive effects were recorded; but trust researchers for their doggedness, they are back at it again.

You may consider transfer factor in prostate cancer treatment as some kind of immunotherapy, which is what it is. Immunotherapy generally seeks to boost the body’s immune system to combat disease. With prostate cancer, it is meant to combat the mutated tumors and kill them before expelling them from the body.

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