Metastatic Prostate Cancer Treatment – How It Works

Metastatic prostate cancer occurs when the cells of the prostate gland mutate, multiply uncontrollably, and start to migrate out of the prostate to other locations in the body. This occurs as the cancerous cells filter into the patient’s bloodstream, invade the lymphatic system, and continue throughout the body, depositing small cancerous cells here and there, which commence to reproduce themselves uncontrollably again. Laymen call it spreading, but the professionals in the business call it metastasis.

For some reasons, metastatic cancers have a preference for the bone so the human skeletal system is very often attacked by the spread of the disease. Soon enough there is sufficient bone pain to perhaps even paralyze the patient if something is not soon done about it. Treatment therefore has to be decisive and aggressive.

To some degree, locally advanced prostate cancers can still be remedied. If the cancer has not metastasized too far from the organ of origin (perhaps still located in the prostate or pelvic regions) it may be possible first to cease, slow, or reverse the progression of the cancer by administering hormonal therapy. Then a combination of brachytherapy and external beam radiation therapy may compel the cancer to go into remission.

If this stage has been passed though, the best that can be hoped for is slowing the progression of the disease, delaying symptoms, managing pain, and generally trying to prolong the life of the patient while also maintaining a reasonable quality of life. To that end, bisphosphnates might be ideal because they have been shown to delay skeletal complications like fractures, which have been known to occur in instances of severe bone metastasis.

Chemotherapy also slows disease progression and postpones symptoms, especially when used with corticosteroids. Certain drugs, many of which are still being studied while awaiting FDA approval, have been shown to cause dramatic reduction in PSA levels in the patients, and even shrink the size of the in aggressive advanced stage prostate malignant cancer.

And on the off chance that the normal pain relievers aren’t working, why, there are still narcotics. Opioid pain relievers like morphine and oxydocone will do great thing for a prostate cancer patient with advanced stage metastatic disease. And if he is looking to live longer still, a late stage prostatectomy or radiation therapy may even double or triple life expectancy.

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