Symptoms Of Late Stage Prostate Cancer- Using Palliative Care To Deal With The Condition
Advanced prostate cancer often spreads to other parts of the body and causes various additional symptoms to the ones that the patient must have been feeling already. The earlier stages of the disease must have been characterized by first no symptoms, but after a while of development and growth frequent and increased urination at night, difficulty starting and maintaining a steady stream of urine, blood in the urine, and painful urination; warning signs that are not too farfetched form the indicators of benign prostate hyperplasia.
Even urinary dysfunction and problems with sexual function and performance may not immediately warn a patient of prostate cancer, especially if he is young and in denial, but difficulties achieving erection or painful ejaculation will likely have him looking to see a doctor.
The most common symptom of later stage prostate cancer is bone pain, which often takes hold in the bones of the spine, pelvis, ribs and other bones like the femur, in the proximal part of the bone. This kind of significant pain in one or more bones often indicates the occurrence of metastases most often in the spine and sometimes flares in the lower back, the hips, or the bones of the upper legs. It may be accompanied by significant weight loss. Such prostate conditionin the spinal column can press hard against the spinal cord and cause leg weakness or paralysis, as well as urinary and fecal incontinence.
There are a number of approaches to dealing with these prostate cancer later stage symptoms most of which essentially boil down to the age of the patient because one may assume at this time that such a disease is hormone refractory in nature by this time. To that end, treatment most likely will constitute the administration of chemotherapeutic drugs like a combination of docetaxel with a corticosteroid such as prednisone that will enter into the body to kill the cancerous cells. Should the patient be well advanced in years, palliative care may well be considered.
Palliative care for advanced stage prostate malignant canceris directed mainly at extending the life of the patient and relieving the symptoms of the metastatic disease. It may require Abiraterone Acetate to cause a dramatic reduction in PSA levels and tumor size, or chemotherapy to slow disease progression and postpone symptoms. Bisphosphonates such as zoledronic acid may delay skeletal (fracture) complications or the need for radiation therapy in patients with this kind of hormone-refractory metastatic prostate cancer; while alpharadin, a new alpha emitting pharmaceutical, would target bone metastasis, prolong patient survival times, reduce pain and improve the quality of life for the cancer of the prostatesufferer.
Especially for the bone pain, opioid pain relievers like morphine and oxycodone should do the trick, although some doctors argue that external beam radiation therapy should be sufficient to provide the needed relief. As an alternative, injections of radioisotopes strontium-89, phosphorus-32, or samarium-153, will also target bone metastases and relieve pain.
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