Testosterone and Prostrate Cancer – Testosterone Therapy after Prostate Surgery

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This article contains important hints about Testosterone and Prostrate Cancer and even specific tips on Testosterone therapy after prostate surgery, even the side effects of prostate cancer hormone testosterone.

First things first, it has been determined for the greater part of a hundred years now that certain forms of cancer have a direct link to hormones in the body, especially cancers of the human reproductive system ? the breast and ovary in females, and cancer of the prostate in men. Testosterone has been specifically implicated in prostate cancer growth and progression, as is its derivative- dihydrotestosterone (DHT).

No one is exactly sure what the cause is for prostate cancer, besides some risk factors for the disorder, namely: age, genetics, race, lifestyle, diet, and certain medications; but there is little question by now that in the presence of the male sex hormones, prostate cancer cells are better able to grow and proliferate. For that reason, one of the most potent treatments for the disorder is to deprive the malignancy of its critical fuel ? testosterone.

Testosterone, the principal male hormone, or androgen, is produced mainly in the Leydig cells of the testes, which also produce other androgens in smaller quantities of less potency. Testosterone primarily is meant to stimulate the development of the male secondary sex characteristics after puberty, causing growth of the beard and pubic hair, development of the penis, and change of voice, while also aiding growth, muscular development, and masculine body contours.

Interestingly, hormone therapy has been found to be very helpful as a hormonal supplement in the treatment of breast cancer in women, which may be interesting because the converse is the case with respect to prostate cancer in males. American scientist and Nobel laureate Charles Brenton Huggins discovered back in the late 1930s that while using dogs as lab rats, their prostate cancer cells grew faster in the presence of testosterone, and once the androgen was done away with, the progression either stopped or was reversed. He won the Nobel Prize for developing on that finding.

Essentially, what it implies today is that one of the known and accepted treatments for prostate cancer, hormonal therapy, involves the manipulation (more suppression) of the testosterone constituent in the male body. This is done either by the surgical removal of the testes which produce the hormone, or its suppression by estrogen supplements, especially synthetic estrogens. There is little doubt that the cancer responds (negatively) to the treatment.

However, testosterone manipulations have been found only to slow the progression of prostate cancer cells in the body, and not cure the condition. After about twelve to twenty months of the application of the treatment, the cancer cells adapt and continue to grow. To that end, it is best to follow up hormonal therapy with either prostatectomy or radiotherapy, or both.

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