Management of Castration-Resistant Prostate Cancer

May 4, 2012 by  
Filed under Prostate Cancer Medication

The type of prostate cancer known as castration resistant prostate is that which has become resistance to hormonal therapy. It has been discovered that androgen/ testosterone increase the risk of prostate cancer in the body. Application of hormonal therapy helps to reduce the volume of these hormones.  However, if after undergoing hormonal therapy, you start experiencing growth of the hormone dependent cancer, then you may need to treat this condition with some measures so as to improve survival.

Here are things you need to know about castration-resistant cancer.

Medications – Some of the best known treatments used to treat castration-resistant prostate cancer (CRPC) include Docetaxel and Cabazitaxel. These drugs have the approvals of the FDA, and have been known to improve the survival rate of the prostate cancer victim. These are often applied as part of the chemotherapy treatment.

Another effective drug for the management of castration-resistant prostate cancer (CRPC) is the oral drug, Ketoconazole and a combination of other drugs like Thalidomide, Bevacizumab, and Prednisone. These have the capacity to manipulate the hormone causing castration-resistant prostate cancer (CRPC). It has been shown that they have minimal side effects. Management of CRPC with these medications has shown to improve the survival rate of patients by more than 4 months.

Apart from some of the chemotherapy treatments mentioned above, immunotherapy treatments have equally shown to be effective in treating castration-resistant prostate cancer (CRPC) and other forms of metastatic prostate cancer. Sipuleucel-T and Abiraterone Acetate are FDA approved immunotherapy that can be applied to treat late stage or metastatic prostate cancer. These can be applied before chemotherapy treatment.

So, the above paragraphs highlight some of the best known treatments for castration-resistant prostate cancer (CRPC). This form of prostate cancer can be deadly and offers the victim little chance of survival. Thankfully, with thorough research efforts the use of drugs and other treatment options has been developed to help manage the symptoms of this condition. People that have been diagnosed with late stage prostate cancer have more to benefit with the treatments.

Conclusively, if you have been diagnosed with prostate cancer and you have been diagnosed with CRPC, then your doctor can provide you details on how your treatment is going to look like. Consult with him to know the treatment options you have and the possible side effects. It is important to still have realistic expectations when it comes to the medications or management of castration-resistant prostate cancer (CRPC).

Understanding the Drugs for Prostate Cancer Treatment

April 29, 2012 by  
Filed under Prostate Cancer Medication

When a person is diagnosed of cancer of the prostate, then what comes on next is to find the most suitable cure. A lot of options are readily available since this condition is classified under a type of cancer diseases that affect men. The general treatments for prostate cancer are related to that which is applied to treat other types of cancer. In this case, surgery (radical prostatectomy), Radiation therapy (Internal or external), hormonal therapy, vaccines, and chemotherapy, etc, could be applied to treat the condition.

Despite the cause of the treatment procedure applied, one fact that will stick is that the high level of the hormone testosterone increases the ability of the cancer cells to grow. Since this hormone promotes cancer growth, most of the drugs produced now tend to inhibit the production of testosterone or androgen in the body. Thus, it is important you have an idea of these drugs and how they really work to frustrate and kill cancer of the prostate gland. The following paragraphs provide you with a list of the drugs that are used in the treatment of this male related cancer. Also, you get to have an idea of when they are may be administered.

List of approved prostate cancer drugs

The Food and Drugs Administration (FDA) of the United States has approved the use of certain drugs or medications for the treatment of cancer of the prostate. This list will help you get idea of what the doctor may recommend for you. The list includes drugs such as:Abiraterone Acetate, Lupron (Leuprolide Acetate),Cabazitaxel, Docetaxel, Prednisone, Sipuleucel-T, Taxotere (Docetaxel), Degarelix, Provenge (Sipuleucel-T), Zytiga (Abiraterone Acetate), and Viadur (Leuprolide Acetate),etc. There are other brands of drugs out there and the internet will help you get more facts about them.

When prostate cancer drugs can be used 

There are so many occasions when prostate cancer drugs can be applied. They can be used as independent medications of used in combinations with other treatments like radiation treatments, and surgery. Chemotherapy and hormonal treatments are two major treatment procedures that require the use of drugs solely to destroy or inhibit tumors on the cells.

As I started above, the objectives of most drugs is to reduce the effects that the testosterone hormone poses to increase prostate cancer. The drug will either cut out the production or reduce the quantity in the body. More so, some of the drugs act to get destroy the cancerous cells completely.

Conclusively, the effects of drugs or medications in prostate cancer have been successfully in many cases. They have helped to increase the survival rate of those diagnosed. Although a permanent cure for this second killer cancer for men has not been discovered, the effects of these drugs have provided relief and hope for victims and their loved ones. So, you can talk to a qualified doctor or visit the Internet for more details on drugs for prostate treatments.

Pills and Medications Effective In Prostate Cancer Treatments

There are actually certain pills that are effective in the treatment of prostate cancer, which are often used in various forms of therapy that are meant to cure the condition or to provide some form of palliation for a patient with advanced stage disease. Some of the more common pills are parts of hormonal therapy for the condition which may be applied either in early stage or advanced prostate cancer.

These pills are meant to interfere with the body’s production of testosterone, dehydroepiandrosterone (DHEA), and dihydrotestosterone (DHT), which in some manner have been implicated as promoting the growth of the disease.

Pills in hormonal therapy include GnRH agonists and antagonists and drugs like toremifene, which has shown promise in early trials; and finasteride and dutasteride, which have been known to block the conversion of testosterone to DHT. And for prostate cancer cells that have proven resistant to hormonal therapies, another drug like abiratone acetate is currently in study, showing great promise in phase II trials, and looking for an early 2011 FDA approval.

According to writer Daniel Martin, British researchers made the dramatic breakthrough against lethal forms of prostate cancer in trials of the new pill that shrinks tumors in up to 80 per cent of cases. The excitement at the possibility of ending the need for damaging chemotherapy and radiotherapy brings with it a heady feeling. Experts hail it as perhaps the biggest advance in prostate cancer research in decades, and team leader, Dr Johann de Bono, thinks patients can control the prostate cancer only four abiratone acetate pills a day, and very few side-effects.

Calcitriol, a pill made from a form of vitamin D, also appears to be doing wonders both in the treatment of prostate cancer, and as a preventive measure for the disease. Calcitriol, already approved as prescription medication, can be taken also without much fear for side effects because it is basically a natural supplement that the body is in need of.

A daily dose reduces PSA levels, an indicator or the severity of the disease, by as much as half in patients diagnosed with advanced stage disease. John Neate of the Prostate Cancer Charity however says that “the role of supplements in the prevention and treatment of prostate cancer is an area which deserves a greater level of research attention.”

And there are drugs like flutamide and casodex, all forms of hormone treatments for prostate cancer, which have their side effects but which may also be used to treat the disease. These medications mostly can only be gotten with prescriptions, so the doctor will have to be handy.

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